What foods are good sources of indoles?

Indole-3-carbinol is formed from a substance called glucobrassicin found in vegetables such as broccoli, Brussels sprouts, cabbage, collards, cauliflower, kale, mustard greens, turnips, and rutabagas. Indole-3-carbinol is formed when these vegetables are cut, chewed or cooked. It can also be produced in the laboratory.

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Does indole-3-carbinol reduce estrogen?

Indole-3-Carbinol for Breast Health Indole-3-Carbinol has been shown to act as a catalyst to decrease the body’s load of unhealthy estrogens and reduce symptoms of estrogen dominance.

Does indole-3-carbinol really work?

It is known to stimulate detoxifying enzymes in the gut and liver. Because diets high in these vegetables slow cancer growth in animals, I3C is thought to be a good candidate for cancer prevention. Lab studies suggest that I3C may have activity across various tumor types, or enhance activity of some chemotherapy drugs.

How much indole-3-carbinol is a serving of broccoli?

Food sources

Food (raw)	Serving	Total Glucosinolates (mg)
Cabbage, red	½ cup, chopped	29
Broccoli	½ cup, chopped	27
Horseradish	1 tablespoon (15 g)	24
Cauliflower	½ cup, chopped	22

Do broccoli sprouts have I3C?

Broccoli sprouts contain high levels of sulforaphane, approximately 20 to 50 times greater than mature broccoli. Indole-3-carbinol (I3C), as well as the nitrile crambene, through different mechanisms, activate detoxification enzymes.

Which is better DIM or I3C?

In summary, we have known for a long time that I3C is partially responsible for many of the beneficial effects of consuming cruciferous vegetables. I3C breaks down to many different active metabolites, but DIM appears to be the most stable, and the most measurable, making it easier to isolate.

Is it better to take DIM or I3C?

Does indole-3-carbinol need to be refrigerated?

Pure Encapsulations recommends taking between 200 mg and 800 mg indole-3-carbinol per day, in divided doses, with meals. This formula requires refrigeration.

Is sulforaphane the same as I3C?

I3C is found in the vegetables of the species Brassica oleracea, which is made up of broccoli, Brussels sprouts, cauliflower, and kale, which possess glucobrassicin, the precursor of I3C and sulforaphane (Z. Li et al., 2017).

Can indole-3-carbinol help lose weight?

These findings suggest that I3C has a potential benefit in preventing obesity and metabolic disorders, and the action for I3C in vivo may involve multiple mechanisms including decreased adipogenesis and inflammation, along with activated thermogenesis.

Is indole-3-carbinol the same as dim?

They do come from the same source, and the majority of I3C is converted to DIM – so much so that DIM can be detectable in your blood shortly after taking I3C. However, DIM and I3C are different molecules with different (albeit similar) chemical structures.

Which foods are indole rich?

Research suggests that eating a diet rich in fruits, vegetables and cereal grains may help to reduce your risk of cancer and other diseases. Cruciferous vegetables provide a rich indole source. These include Brussels sprouts, broccoli, bok choy, cabbage and turnips.

What is indole 3 carbinol made from?

Overview Information. Indole-3-carbinol is formed from a substance called glucobrassicin found in vegetables such as broccoli, Brussels sprouts, cabbage, collards, cauliflower, kale, mustard greens, turnips, and rutabagas. Indole-3-carbinol is formed when these vegetables are cut, chewed or cooked.

Can indole-3-carbinol be taken with other medications?

Taking indole-3-carbinol along with some medications that are changed by the liver can decrease the effectiveness of some medications.

Can indole-3-carbinol be used long term for papillomatosis?

Recurrent respiratory papillomatosis. There is some evidence that long-term use of indole-3-carbinol might reduce tumor (papilloma) growth in people with recurrent respiratory papillomatosis. Systemic lupus erythematosus (SLE).